Sciensano conducts various electron microscopic analyses using transmission electron microscopy (TEM). These include the identification of nanomaterials according to the EC definition (2011/ 696/ EU), the detailed characterization of nanomaterials as part of risk assessments, classification and toxicological evaluation and characterization of virus-like particles.
Our TEM analysis service for the identification & characterization of (nano)particles encompasses the following:
- Sample preparation (dispersion) of powder samples:
- NANoREG protocol
- Guiot & Spalla protocol
- Tailor-made sample preparation
- PTA analysis of nanomaterials in a stable dispersion
- DLS analysis of nanomaterials in a stable dispersion
- Zeto potential measurement of nanomaterials in a stable dispersion
- Preparation of TEM specimen and descriptive TEM characterization (assuming stable dispersion)
- Advanced TEM characterization
- Quantitative
- TEM characterization of aggregates / agglomerates (image recording and analysis)
- TEM characterization of primary particles (image recording and analysis)
- Diffraction
- Crystal structure (powder electron diffraction)
- Quantitative
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